Tag: permissive substitution

Mandatory vs Permissive Substitution: How State Laws Control Generic Drug Switching

Posted By Simon Woodhead    On 28 Jan 2026    Comments(1)
Mandatory vs Permissive Substitution: How State Laws Control Generic Drug Switching

Mandatory and permissive substitution laws determine whether pharmacists must or can switch brand-name drugs to cheaper generics. These state-by-state rules impact costs, adherence, and access-and they vary dramatically across the U.S.